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Hence, both exercise, especially moderate anaerobic physical exercise, and a healthy diet rich in plant-derived nutrients, can positively affect PD incidence and progression, by stimulating neurotrophic factors, altering the diversity of the gut microbiome, improving barrier permeability, and increasing the levels of SCFAs- producing bacteria (Raber and Sharpton, 2023)
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Quercetin can also alleviate experimental colitis by modulating macrophage’s anti-inflammatory and bactericidal activities via an HO-1-dependent pathway, and administering it through diet could help restore intestinal balance and promote healthy gut microbiota as a potential IBD treatment (97)