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Dysregulated Intracellular Signaling in the Pathogenesis of Vitiligo: An Update on Emerging Therapeutic Strategies

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In tumor-associated epilepsies such as glioblastoma, xCT overexpression and elevated peritumoral glutamate concentration were associated with seizure generation and complications in patient survival [59–61] while treatment with xCT inhibitors such as sulfasalazine decreased epileptiform activity in vivo and in vitro [62]