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In many cases, the drugs make depressed individuals feel worse, and FDA-mandated labeling now requires a warning that use of some antidepressants increases suicide risk.(4,5) Maurizio Fava, MD, vice chair of the department of psychiatry and director of the Depression Clinical and Research Program (DCRP) at Massachusetts General Hospital, noted in a recently published study that the majority of depressed patients will not experience remission when treated with a first-line antidepressant

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