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IL-6 IL-6 is produced under a variety of stimuli including tissue damage, viruses, or other proinflammatory cytokines

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upregulated lysine and leucine transfer RNA ligases), proteasomal degradation (e.g., upregulated E3 ubiquitin-protein ligase NEDD4), detoxification of reactive oxygen species (e.g., downregulated superoxide dismutase), and motor nerve regeneration (e.g., upregulated β-taxilin)