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One of the ten subjects developed acne one week after vitamin B12 supplementation Consistent with multiple clinical studies previously reporting that vitamin B12 supplementation induces acne in subsets of individuals ( 20–26 ), in the current study, one of the ten healthy subjects, HL414, had multiple erythematous papules and comedones developed on the face one week after vitamin B12 supplementation (Supplementary Materials)

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Adding Thymosin Alpha-1 extends this approach by incorporating immune support, particularly valuable for those recovering from surgery or dealing with chronic health challenges