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The liposome system relies on a dual pH-responsive peptide (DPRP), which is primarily composed of three components: a cell-penetrating domain-octa-arginine, a polyanion shielding domain- ehGehGehG, and a pH-responsive imine bond connecting the above two components
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By integrating lipidomics with transcriptomic analyses, the authors showed that defective lipid class switching may contribute to persistent tumor-associated inflammation and colorectal cancer progression (Soundararajan et al., 2025)
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