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We found that the transcriptional activity of SERPINE1 was significantly higher in the cells co-transfected with WT TP53 and LCRMP-1 plasmids compared to those only transfected with LCRMP-1 or co-transfected with mutant-type TP53 (R248W) and LCRMP-1 (Fig
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For example, it is the underlying cause of the well-known neurotoxicity induced by cisplatin (Cis-DDP), which often leads to the discontinuation of chemotherapy based on Cis-DDP
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