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doi: 10.1016/j.schres.2017.07.008

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There are multiple interesting PPIs in the Wnt signaling pathway, notably β-catenin/TCF and β-catenin/Bcl9, for which there are several reported small-molecule 201,202 and macrocyclic peptide binders (particularly stapled peptides), 203 although these were generally obtained from rational structure-based design rather than NELS campaigns