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In a rat lung fibrosis model induced by BLM, dexamethasone (positive control group) and rutin significantly reduced the protein expression rates of fibrosis biomarkers (a-SMA, collagen I and collagen III) and TGF-β1, improved bleeding, thickening of alveolar septa, infiltration of alveolar wall cells, and necrosis of alveolar tissue

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However, it does not contain dynamic processes and topics, including the network and complexity of biological systems’ interactions