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Accordingly, serum levels of MDA, a marker of lipid peroxidation, have been described as presenting positive correlation with proinflammatory cytokines in RA [28], with reactive oxygen metabolites (ROM) in blood samples also found to be increased in patients with RA and positively correlated with disease activity [61]
gltathione
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In cystine-limited conditions, T cells experience GSH depletion (Figure 4), rendering them incapable of neutralizing accumulating lipid peroxides and predisposing them to ferroptotic cell death
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