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5-Amino-1MQ wird als NNMT-Inhibitor untersucht, der in Forschungsmodellen zur Erhaltung des NAD+-Salvage-Wegs beiträgt, und MOTS-c ist ein aus den Mitochondrien stammendes Peptid, das mit der AMPK-Aktivierung und der metabolischen Homöostase in Verbindung gebracht wird (Lee et al., 2015, Cell Metabolism)
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