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It is noted that “indeterminate phase” patients have a higher risk of disease progression compared to true HBeAg-positive chronic HBV (formerly known as the immune tolerance phase) or HBeAg-negative chronic HBV (formerly known as inactive HBsAg carrier status) patients, and antiviral therapy might be required
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Before the addition of multivalent cations or chelators, all solutions were treated with the metal-chelating ion exchange resin Chelex 100 to remove adventitious metal ions
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