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Analyzing a series of studies using differing amounts of B12 via injection, the IOM determined that 1.5 µg of absorbed B12 per day was enough to normalize red blood cell parameters (hematocrit, red blood cell volume, and anemia) in the average patient with pernicious anemia
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These deficiencies can occur due to inadequate dietary intake, malabsorption issues, certain medical conditions, or medications that interfere with B vitamin absorption
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