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So the useful question is not “does it work.” It is “what was actually measured, in whom, and how.” The rest of this guide answers that

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Indeed, in comparative analyses, where GSSG was determined after treatment of blood aliquots with either 2-VP or NEM, the levels of GSSG were at least 12 times higher in 2VP-treated samples with a corresponding decrease of the GSH/GSSG ratio [14]