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3.1 Intestinal flora as a basis for the functioning of the intestinal mucosal barrier The intestinal tract of healthy adults contains approximately 10 13 to 10 14 microorganisms with a complex structure that is influenced by factors such as genotype, diet, age, disease, and lifestyle ( Bifidobacterium bifidum , Lactobacillus lactis ) can defend against pathogen invasion, synthesize vitamins, produce a number of enzymes, and participate in nutrient metabolism, and can form an intestinal biobarrier through the phosphoric acid wall and interconnection with the human intestinal mucosa to prevent invasion of harmful microorganisms or toxins, which constitutes a biobarrier (Wu et al., 2023)

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D., Penning, T