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Indeed, clinical reports show promising results with BRAF V600E inhibitor therapy in optic pathway glioma ( V600E mutation in pediatric, infantile, and adult LGGs ( V600E ) have been associated with poor prognosis in pediatric LGG when all sites and histologies were included ( In conclusion, BRAF V600E -altered CNS tumors occur in diverse neuroanatomical locations, predominantly in hemispheric areas and BRAF V600E -altered PA exhibit a strong association with extra-cerebellar location
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Molodecky NA, Soon IS, Rabi DM, Ghali WA, Ferris M, Chernoff G, et al
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