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Metabolite pool and Isotopomer Labelling Analysis For cell metabolic analysis, SNU638 cells were incubated with RPMI-1640 medium (glucose free or glutamine free), supplemented with 10% dialyzed FBS and 11 mM [U 13 C]-glucose or 4 mM [U 13 C]-glutamine for 24 h

Ernährungsform:vegetarisch

mg:10mg

GCH1-mediated defense mechanism GTP cyclohydrolase-1 (GCH1) is the rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin (BH4), a critical cofactor necessary for various biochemical processes, including the synthesis of monoamine neurotransmitters and the regulation of nitric oxide levels (178,179)