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Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents
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This study was designed to (1) establish a reproducible dual-induction animal model of male infertility combining endocrine disruption and oxidative stress, and (2) evaluate the dose-dependent therapeutic effects of NAC using functional, biochemical, and histopathological endpoints within a translational research framework
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