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Whilst indistinguishable in many respects, these empty capsids are inherently less stable than an infectious virus and prone to switching conformation from the native D-antigenic state to the less immunogenic C-antigenic structure 12
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Among the retreated patients, severe flares is the only predictor for HBeAg loss [rate ratio: 6.15 (95% CI: 2.7-14.01, p 3.25 (22.6% vs
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