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For the most part, the protein has limited amino acid sequence homology to other Prdxs, and Clustal analysis indicates divergences of Prdx6 (and Prdx5) from the more conserved Prdx1–4 (Fig
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310,311 A research review noted that women who suffered from PMS during their reproductive years had a greater chance of having hot flashes during their peri- and postmenopausal years
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