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GPX7 has two unique endoplasmic reticulum secreted proteins, the N-terminal endoplasmic reticulum signaling peptides (HGPX7 and MGPX7) and the C-terminal atypical KDEL sequence (endoplasmic reticulum recovery signaling) (Raykhel et al., 2007)
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The findings suggest that AST can strengthen the antioxidant defense system and mitigate neuroinflammation induced by DOX (El-Agamy et al., 2018)
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