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Marketed under the brand name Antabuse ® , the medication fosters abstinence by inducing the adverse effects associated with alcohol consumption (e.g., nausea, headache, emesis)
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Inhibition of VPA β-oxidation by salicylate was sufficient to counterbalance the increased elimination of VPA in the form of its conjugates and explain why the total clearance of VPA after administration of this salicylate remains unchanged, even if the free fraction of VPA increases
The liquid format is a convenient option for those who prefer not to use capsules or powder
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