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(C-E) qRT-PCR was used to detect the mRNA expressions of IL-1β, IL-8, and TNFα in MSU-induced THP-1 cells after knocking down IL1A
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3.2.7 Other PD-related genes/proteins potentially associated with ferroptosis The absence of CISD1, an iron-rich outer mitochondrial membrane protein, triggers mitochondrial dysfunction alongside the depletion of striatal dopamine and TH, thus facilitating the advancement of PD and the worsening of its clinical manifestations (172)
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