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doi: 10.3390/ani10050895 171 KimS
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hence, higher intracellular Zn levels may boost PARP activity, and further, Zn overload increases intracellular ROS in an NADPH oxidase-dependent way, suggesting that ROS generation may contribute to zinc-induced PARP activation (Figure 4A) [70,100,101,102,103]
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