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The efficacy population comprised patients who received single-agent dordaviprone for diffuse midline glioma harboring an H3 K27M variant and had progressive and measurable disease per Response Assessment in Neuro-Oncology–High Grade Glioma (RANO-HGG) criteria
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78 The enzyme glutaminase in the liver breaks glutamine into glutamate and ammonium ions, which are excreted as urea through urine
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