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While researchers commonly tag a protein to purify it from a cellular lysate and use the isolated protein in biochemical assays, a peptide tag can do more
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Hypophysectomized rats show a rapid increase in serum IGF1 after recombinant human GH (rhGH) administration, and a 75% reduction of circulating IGF1 levels due to the liver IGF1-deficient in mice leads to a fourfold increase in GH secretion (Yakar et al., 2004)
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