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There are indeed first attempts to use cerebral organoids for exploring the effects of glucocorticoids on early human brain development, mimicking early-life stress exposures [246] as well as the use of human hippocampal progenitor cells to test the effects of specific nutrients [247, 248] and of how fatty acid exposure interacts with glucocorticoids [249] on the neurogenic process
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We hypothesized ALC treatment during critical periods in cortical development would promote normal synaptic maturation, and continuing treatment would improve behavioral deficits in the Mecp2 1lox mouse model of RTT
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