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[ 404 , 405 , 408 , 409 , 410 , 411 , 412 , 413 , 414 , 415 , 416 , 417 , 418 ] The unfolding forces of proteins typically remain relatively low, often in the range of a few hundred piconewtons, owing to the presence of weak interactions such as hydrogen bonds, cation‐π interactions, and ionic bonds
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FIGURE 3 3.1 Activation of the mTOR signaling pathway BCAAs, particularly leucine, activate the mTORC1 (mammalian target of rapamycin complex 1) pathway by directly binding to it
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