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There is a minor role for DORs in regulating VTA GABA transmission under normal conditions, but as in other brain regions, DOR-mediated inhibition of GABA transmission is inducible by in vivo drug exposure (Margolis et al., 2008a
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LSH, a member of the chromatin remodeling ATPase SNF2 family, establishes the correct levels and patterns of DNA methylation, maintains the stability of the genome in mammalian somatic cells, and is essential for normal development (Fan et al., 2003
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