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It is unusual among peptides because the first bond is a gamma linkage from the glutamate side chain rather than a standard alpha peptide bond, which is why it resists ordinary peptidases and is synthesised enzymatically rather than on a ribosome

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On average, the injection’s effects can last anywhere from a few days to a few months, depending on factors like a patient’s treatment plan, adherence to it, and the extent of the underlying condition