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[ CrossRef ] [ Google scholar ] [ PubMed ] Pickart L, Vasquez-Soltero JM, Margolina A

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Using in vitro assays that reconstitute β-catenin phosphorylation at residues S33, 37, and 41 (the former two being recognized by the E3 ubiquitin ligase, β-TrCP), these groups present evidence that a phosphorylated LRP6 PPPp S PXp S peptide directly inhibits β-catenin phosphorylation by GSK3 at S33, S37, and T41

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