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Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism
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MAB-stimulated granulomas have Th1 and Th17 inflammatory profiles dominated by IL-7 (2-fold), IL-7R (2-fold), and IFN-γ expression (1,4-fold)
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