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It can also affect immunosuppressants such as cyclosporine and some antipsychotics
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For instance, enterotoxin peptide derivatives like cholix toxin and zona occludens toxin (Zot), derived from the Gram-negative bacterium Vibrio cholerae , can reversibly increase paracellular permeability by activating intracellular signaling pathways that modulate actin polymerization [112] Similarly, other enterotoxin peptides and their derivatives include the Clostridium perfringens enterotoxin peptide and melittin facilitates the transcellular transport of proteins [113,114]
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