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Studies have consistently demonstrated a strong correlation between ferroptosis, iron accumulation, and heme dysregulation in SCD (Ashouri et al., 2021, Gbotosho et al., 2021)
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Not only is there a U-shaped curve with insufficient iodine causing hypothyroidism and excessive iodine causing hyperthyroidism, but also introduction of iodine supplementation programs can enhance autoimmunity and change the pattern of thyroid diseases in a country
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