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Usage Instructions B12 Injections are self-injected 1-2 times per week, with or without food, according to your provider-guided titration schedule

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Pack Size:60 Patches - 2 month supply - SAVE £10!

Bioregulator theory and mechanism Khavinson's bioregulator concept: Each organ produces specific regulatory peptides These peptides maintain tissue homeostasis With aging, peptide production declines Supplementing organ-specific peptides restores function Gene regulation is key mechanism How Cartalax works (theory): Enters cartilage cells (chondrocytes) Binds to specific DNA sequences Upregulates cartilage-protective genes Downregulates degradative genes Optimizes cartilage matrix production Gene expression changes: Upregulated (increased): Collagen Type II: Main cartilage structural protein Proteoglycans: Water-holding molecules Aggrecan: Cartilage compressive strength TGF-β: Growth factors for cartilage Chondrocyte proliferation genes Downregulated (decreased): Matrix Metalloproteinases (MMPs): Cartilage-degrading enzymes Inflammatory cytokines: IL-1β, TNF-α Apoptosis genes: Prevents cartilage cell death Oxidative stress markers Mechanism comparison: Why bioregulation different: Works at DNA/gene level (root cause) Tissue-specific (only cartilage affected) Long-lasting effects (genes stay regulated) Cyclic dosing sufficient (vs continuous) Preventive and restorative Compare to other mechanisms and joint peptides