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Meanwhile, a longitudinal cohort study should be carried out to correlate the dynamics of the patients’ gut microbiota, the levels of serum gut metabolites with the progression of joint ferroptosis

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Sub-acute toxicity of MO leaves using an aqueous extract showed signs of mild organ toxicity, as seen based on an increase in WBC, chloride, potassium, calcium ions (Cl − , K + , and Ca 2+ ) concentrations, an increase in the average ALP (alkaline phosphatase), ALT (alanine aminotransferase), AST (alanine aminotransferase), and total bilirubin (Kasolo et al., 2012)