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A glyoxal-specific aldehyde signaling axis in Pseudomonas aeruginosa that influences quorum sensing and infection | Nature Communications

In chronic stress responses and depression, the persistent activation of the HPA axis and the sympathetic‐adrenal‐medullary axis impairs the immune response, including high concentrations of circulating neutrophils and weakened neutrophil phagocytosis, resulting in the progression of various tumors from experimental animal models, human studies, and clinical evidence [91]

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Ultimately, apoptotic cells are ingested by neighboring cells and phagocytes, preventing inflammation and tissue damage that might ensue on cell lysis