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In the TME, multiple factors contribute to immune suppression, including low oxygen and pH levels, limited nutrient availability (e.g., glucose, fatty acids, and amino acids), accumulation of immunosuppressive metabolites (e.g., ROS, lactate, and lipids), and increased secretion of immunosuppressive cytokines as well as chemokines [6,7,8]
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Size:10ml / 0.33 fl oz
Even after treatment, melasma can return when triggered by certain factors
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