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Ignited by the observation of a rapid antidepressant effect of the glutamate N -methyl-D-aspartate (NMDA) receptor antagonist ketamine, the glutamate system has emerged as a leading focus for novel drug discovery for depression and other mood disorders
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Yeast surface display A technique whereby proteins or peptides are expressed on the surface of Saccharomyces cerevisiae (yeast) cells, enabling the screening or selection of binding interactions, such as antibody–antigen or enzyme–substrate in high-throughput assays
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