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In recent studies pediatric renal transplant patients who carried the UGT2B7*2 variant (either homozygotes or heterozygotes) were found to clear mycophenolate less efficiently than wild-type subjects

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The substantially higher levels of liver GSSG observed with the established [10, 11] 2VP methods (Figure 5), compared with our values using M4VP masking, suggest an autooxidation and/or less than quantitative masking of GSH by the 2VP methods