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When TTP is suspected because of hemolytic anemia accompanied by significant schistocytosis, it is important to consider pseudo-TMA due to vitamin B12 deficiency as a differential diagnosis

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Capacity:30 G

With regard to depression, we have few and inconclusive studies, although we would like to point out that one study on patients with a major depressive episode, who had a chronic psychiatric disorder (on average, for almost 17 years) and therefore had a poor response to pharmacological treatment, concluded that supplementing standard treatment with NAC has favorable effects by reducing symptoms and improving patients’ functioning [129]