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NADPH The body leans more heavily on NADH when it needs energy, like during physical activity, when cells are breaking down nutrients, or when the mitochondria are working overtime to produce ATP
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2 Pathogenesis of DCM DCM is usually characterized as a contractile dysfunction with later onset of HF without association to dyslipidemia, hypertension or coronary artery disease, but instead caused by metabolic and humoral disruption in connection with hyperglycemia, hyperinsulinemia and insulin resistance ( The two main factors that drive DCM are long-term hyperglycemia and insulin resistance
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