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Pechácek et al [22] studied AITC hydrolysis in an alkaline solution at a high temperature, 80°C, and concluded that, in addition to allylamine, diallylthiourea, and carbon disulfides, the newly identified major products were allyl dithiocarbamate and diallyl sulfides
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These molecules activate immune-sensing pathways in microglia, including TLR4, P2X7, and cGAS–STING, leading to the robust release of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) (Ayton et al., 2013)
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