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The exclusion criteria for this study were as follows: (i) a current condition and/or disease of the skin that the investigator deemed inappropriate for participation, (ii) women who were nursing, pregnant, or planning to become pregnant during the study, (iii) a preexisting or dormant dermatologic conditions that could interfere with the outcome of the study, (iv) regular consumption or application of antioxidants, that is, vitamin C, CoQ10, and polyphenol extracts, (v) significant history of heart failure, dyslipidemia, diabetes, or uncontrolled hypertension, (vi) risk of food allergy, (vii) extreme skin condition changes caused by menstruation, (viii) current participation in another facial usage study or prior participation in a clinical trial within 4 weeks prior to inclusion into the study, (ix) planned surgeries and/or invasive medical procedures during the course of the study, (x) hormone replacement therapy (HRT) or hormone birth control use initiated less than 3 months prior to study entry or planned for cessation during the study, (xi) facial sunburn or excessive tanned facial skin or lack of willingness to avoid daily facial sun exposure or cease tanning bed or sunless tanning product use for the duration of the study, (xii) currently prescribed or history (within the last 30 days) of oral or topical probiotics or antibiotics, and (xiii) history of psychiatric disorders that may impair the subjects' ability to provide written informed consent
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