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Epithalon is discussed partly because of its association with pineal signaling and melatonin pathways in certain studies
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Nowadays, the regimens of cancer therapy, such as surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy, aim to induce the death of cancer cells to achieve a therapeutic effect, whereas the intrinsic and acquired resistance of cancer cells to cell death often results in far from satisfactory treatment outcomes (Loftus et al., 2022
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