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Increased carbamylation has been linked to complications of chronic renal diseases, including renal fibrogenesis, cataracts, and rheumatoid arthritis [66,67]
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They optimized ncAA incorporation efficiencies by implementing synonymous codon substitutions flanking the amber stop codon, guided by iPASS and achieved 1.4 to 5.3-fold of incorporation efficiency increase in HEK293T cells
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