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Given that SASP factors influence these(Campisi, 2013), it will be particularly interesting to determine whether FOXO4-DRI affects those p53-wt cancer cells that have adopted a more migratory and stem-like state due to reprogramming by chronic SASP exposure
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These primary cell lines include stem cells (embryonic stem cells and induced pluripotent stem cells), satellite cells (myoblasts), fibroblasts, and epithelial cells (Guan et al., 2021
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