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Similarly, environmental enrichment, which provides enhanced sensory, cognitive, and motor stimulation, can elevate BDNF levels and, when combined with therapies that bolster TrkB expression (as demonstrated with the peptide P42 in an HD mouse model), synergistically delays disease progression and improves motor and cognitive outcomes (Couly et al., 2021)
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02 Growth Hormone Receptor Signaling Published research has investigated whether AOD-9604 interacts with the classical growth hormone receptor (GHR) or alternative signaling mechanisms
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