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To analyze the phosphorylated NF-κB, NF-κB, and MRP2 expressions in EC109DDP cells, cells were seeded and cultured for 24 h, followed by treatment with PBS, 10 μM CDDP, 150 μg/mL HCFe nanozyme, 150 μg/mL HCFe nanozyme + 10 μM JSH-23, 150 μg/mL HCFe nanozyme + 5 mM NAC, 10 μM CDDP + 150 μg/mL HCFe nanozyme, 10 μM CDDP + 150 μg/mL HCFe nanozyme + 10 μM JSH-23, and 10 μM CDDP + 150 μg/mL HCFe nanozyme + 5 mM NAC for another 24 h