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ASXL1 peaks were primarily promoter localized ( ~ 70%), and BRD4 and ASXL1 co-bound genomic sites had substantial overlap with the marks of active promoters, H3K4me3 and H3K27ac (Fig

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While these registered trials are encouraging indicators of increasing clinical activity, none are examining specific named peptide compounds in isolation, making it impossible to draw peptide-specific conclusions from their eventual results